The Google-Like Application for Metabolic Maps (GLAMM) has been developed to provide an interactive browsing experience with metabolic networks based on that used with web mapping technology. GLAMM is integrated with the MicrobesOnline.org web resource, allowing a researcher to access the many powerful comparative genomic and functional analysis tools present in MicrobesOnline. Visit GLAMM.
FastTree infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. FastTree can handle alignments with up to a million of sequences in a reasonable amount of time and memory. For large alignments, FastTree is 100-1,000 times faster than PhyML 3.0 or RAxML 7. FastTree is open-source software — you can download the code […]
DNA-Tailor (D-Tailor) is a fully extendable software framework for biological sequence analysis and multi-objective sequence design. D-Tailor permits the seamless integration of an arbitrary number of sequence analysis tools into a Monte-Carlo algorithm that evolves synthetic sequences towards user-defined goals. Visit D-Tailor.
The Ecosystems and Networks Integrated with Genes and Molecular Assemblies (ENIGMA) Scientific Focus Area that we help lead is dedicated to developing a generalizable approach to predictive causal microbial ecology. We seek to molecularly dissect the dispersal, drift, and selective forces that shape the assembly and activity of microbial communities in complex spatially and temporally variable niches.
The Center for the Utilization of Biological Engineering in Space (CUBES) was created to develop generalizable approaches to support biomanufacturing for deep space exploration that realizes the inherent mass, power, and volume advantages of space biotechnology over traditional abiotic approaches.
Our lab has been involved in Synthetic Biology since its inception developing fundamental genetic technologies for precise and predictable control of gene expression, uniform design of gene expression networks, technologies for genome-scale manipulation and characterization of gene function; the design of host strains optimized for engineering for different applications; and foundational genetic and computational/data science technologies that support the creation of biofoundries.
